2 Sources of Cholesterol
 
Important Risk Information About VYTORIN (ezetimibe/simvastatin) | Patient Information | Prescribing Information | For Health Care Professionals
 
VYTORIN Treats the 2 sources of cholesterol
The 2 Sources of Cholesterol
Food & Family
Learn more about food & family, the 2 sources of cholesterol.
Learn how to treat the 2 sources of cholesterol, food & family.
Let’s start with a fact that may surprise you. Did you know your cholesterol comes from 2 sources? That‘s right, not only does cholesterol come from food, but it also has a lot to do with your family history.

This may explain why your LDL (bad) cholesterol could still be high, even though you’re trying hard to lower it with diet and exercise.

When diet and exercise aren‘t enough, adding VYTORIN can help. Ask your doctor if VYTORIN is right for you.
VYTORIN contains two cholesterol medicines, Zetia (ezetimibe) and Zocor (simvastatin), in a single tablet. VYTORIN has not been shown to reduce heart attacks or strokes more than Zocor alone.

Important Risk Information About
VYTORIN (ezetimibe/simvastatin)
VYTORIN is a prescription tablet and isn't right for everyone. This includes anyone taking certain medicines or foods that may increase your risk of serious muscle problems with VYTORIN. These medicines include certain antifungals and antibiotics, HIV protease inhibitors, certain hepatitis C virus protease inhibitors, nefazodone, gemfibrozil, cyclosporine, and danazol. So, tell your doctors about any other medications you are taking. VYTORIN also isn't right for people who are allergic to any of its ingredients, women who are nursing or pregnant or who may become pregnant, and anyone with liver problems.

Unexplained muscle pain or weakness could be a sign of a rare but serious side effect and should be reported to your doctor right away. This side effect can rarely cause kidney damage that can lead to death. Also notify your doctor if you have muscle problems that do not go away even after your doctor has advised you to stop taking VYTORIN. The risk of serious muscle problems is greater with higher doses of VYTORIN, particularly the highest dose (10/80 mg). The highest dose should only be used by people who have been taking it chronically (such as 12 months or more) without having muscle damage and who don't need to take certain other medicines.

Your doctor should do simple blood tests to check for liver problems before treatment with VYTORIN and if you have symptoms of liver problems during treatment. Tell your doctor right away if you feel tired or weak or if you have loss of appetite, upper belly pain, dark urine, or yellowing of your skin or the whites of your eyes. Side effects of VYTORIN included headache, muscle pain, and diarrhea.

For more information, see FAQs About VYTORIN.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch
or call 1-800-FDA-1088.

Please read the Patient Information for VYTORIN and discuss it with your doctor. The physician Prescribing Information also is available.

This site is intended only for residents of the United States, its territories, and Puerto Rico.

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