Heart Disease
 
Important Risk Information About VYTORIN | Patient Product Information | Prescribing Information | For Health Care Professionals
VYTORIN treats the 2 sources of cholesterol
Risk Assessment Tool
Are you at risk of heart disease? This educational tool can help prepare you for a discussion with your doctor to determine your risk of heart disease. And, when needed, it may help your doctor determine a treatment plan that’s right for you.

The following risk assessment tool is based on guidelines established by the National Cholesterol Education Program (NCEP) (part of the National Institutes of Health [NIH]).* This tool can estimate your risk of heart disease within the next 10 years.

To determine your risk of heart disease and to learn what your cholesterol goal could be, answer the following questions and click the CALCULATE button. You will be able to print your results and discuss them with your doctor. If you don’t know the answers to any of these questions, be sure to ask your doctor.
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VYTORIN contains two cholesterol medicines, Zetia (ezetimibe) and Zocor (simvastatin), in a single tablet. VYTORIN has not been shown to reduce heart attacks or strokes more than Zocor alone.

If you have
You are in risk category
LDL-C goal
(mg/dL)
heart disease, diabetes, or
risk score of more than 20%
l. Highest risk
<100
2 or more risk factors and risk score of 10% to 20%
ll. Moderately high risk
<130
2 or more risk factors and risk score of less than 10%
lll. Moderate risk
<130
0 or 1 risk factor
lV. Low-to-moderate risk
<160
This information is provided for educational purposes and is not a substitute for medical advice from your physician.

Your doctor or health care professional can give you a more detailed explanation—and personal recommendation—about what your cholesterol numbers should be. But the most important thing to do at this point is to take action.

* NCEP Expert Panel. Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Bethesda, Md: National Heart, Lung, and Blood Institute, National Institutes of Health; 2001. NIH publication 01-3670.
VYTORIN contains two cholesterol medicines, Zetia (ezetimibe) and Zocor (simvastatin), in a single tablet. VYTORIN has not been shown to reduce heart attacks or strokes more than Zocor alone.

Important Risk Information About VYTORIN
VYTORIN is a prescription tablet and isn‘t right for everyone, including women who are nursing or pregnant or who may become pregnant, and anyone with liver problems.

Unexplained muscle pain or weakness could be a sign of a rare but serious side effect and should be reported to your doctor right away. VYTORIN may interact with other medicines or certain foods, increasing your risk of getting this serious side effect. So, tell your doctor about any other medications you are taking.

Your doctor may do simple blood tests before and during treatment with VYTORIN to check for liver problems. Side effects included headache, muscle pain, and diarrhea.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please read the Patient Product Information and discuss it with your doctor. Also available is the physician Prescribing Information.
20950092(1)-08/09-VYT